Core Immunity Kit – Evidenco

Core Immunity Kit

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Core Immunity Kit: Featuring Immunofree, enriched with global herbs renowned for enhancing immunity and lung vitality, paired with Reginmune, Europe's favored bioregulator for immune stability and energetic harmony.

Immunofree: This blend encapsulates globally-sourced herbs, scientifically supported for their capabilities in fortifying immunity, promoting lung health, ensuring anti-coagulation, and shielding organs. Regions like China, Madagascar, and select Indian states have mandated the use of some of these herbs.

Reginmune (Known as Optimune in Europe): A state-of-the-art bioregulator designed to uplift the body's nutritional and energetic equilibrium while amplifying immune response. Its action is postulated to:

  • Uphold the inherent processes governing natural immune moderation, revitalizing homeostatic balance mechanisms.
  • Streamline the energy and defense systems, correcting imbalances in humoral and cellular immunity.
  • Coordinate a select ensemble of vital amino acids to guide the body's innate immune regulation pathways.

    Ingredients

    Immunofree:

    1. Kalmegh Andrographis panicullata Whole plant 40
    2. Bhunimbha Phylanthus niruri whole plant 40
    3. Yastimadhu Glycirhizza glabra Root 40
    4. Tulsi Ocimum sanctum aerial part 30
    5. Guduchi Tinospora cordifolia Ghana satwa 40
    6. Pushkarmool Inula racemose Root 30
    7. Rasna Alpinia galangal Root 20
    8. Draksha Vitis Vinifera Fruit/seed ext 20
    9. Haridra Curcuma longa Rhizome 10
    10. Haritaki Terminalia chebula Fruit 20
    11. Kumari Aloe barbandensis Leaf 20
    12. Shilajit- Asphaltum Mineral 20
    13. Jasad Bhasma Oxide of zinc Powder 20
    14. Pippali Piper longum fruit 5
    15. Damanaka/Damar Artemisia nilagirica 40

    Reginmune:

    Each capsule contains:

    • Group I -Phytotheraputic Plant Extracts: Echinacea extract (Echinacea purpurea, 4.0% total polyphenols) 80mg, Aloe vera80 mg, Cat’s Claw extract (Uncariatomentosa, bark, more than 3.0% alkaloids) 80 mg.
    • Group II- Amino acids: L- glutamine 140mg, L-arginine 80 mg, L-lysine HCl 40 mg, L- Isoleucine 20 mg.
    • Group III- Vitamins and minerals: Magnesium gluconate (5.86 %magnesium) 40 mg, Copper gluconate (14.44% copper) 3.5mg, Zinc gluconate(14.35% zinc) 25 mg.
    • Group IV- Biopolymer in the cellular matrix: Sodium hyaluronate 7.5 mg.

     

    Research Studies on Ingredients of Immunofree

    1. Kalmegh (Andrographis panicullata) Whole plant

      • Features: Contains andrographolide, a potent compound known for its immune-modulating effects1.
      • Benefits: Enhances immune response and may offer liver protection.

    2. Bhunimbha (Phylanthus niruri) Whole plant

      • Features: Rich in lignans, flavonoids, and ellagitannins2.
      • Benefits: Supports liver health and has immune-enhancing properties.

    3. Yastimadhu (Glycirhizza glabra) Root

      • Features: Contains glycyrrhizin, which has antiviral and anti-inflammatory properties3.
      • Benefits: Boosts immune function, soothes respiratory issues, and offers gastroprotective effects.

    4. Tulsi (Ocimum sanctum) Aerial part

      • Features: Contains eugenol and ursolic acid4.
      • Benefits: Offers immune-boosting, anti-inflammatory, and adaptogenic properties. Promotes lung health.

    5. Guduchi (Tinospora cordifolia) Ghana satwa

      • Features: Packed with immunomodulatory compounds5.
      • Benefits: Enhances immune function and may provide organ protection, especially for the liver.

    6. Pushkarmool (Inula racemose) Root

      • Features: Known to contain sesquiterpenes6.
      • Benefits: Supports respiratory health by dilating bronchioles.

    7. Rasna (Alpinia galangal) Root

      • Features: Contains anti-inflammatory compounds.
      • Benefits: Supports joint and muscle health.

    8. Draksha (Vitis Vinifera) Fruit/seed ext

      • Features: Contains flavonoids and antioxidants.
      • Benefits: Immune-boosting, supports heart health, and may have anticoagulant properties.

    9. Haridra (Curcuma longa) Rhizome

      • Features: Contains curcumin, known for its anti-inflammatory properties7.
      • Benefits: Boosts immune function and promotes overall organ health.

    10. Haritaki (Terminalia chebula) Fruit

      • Features: Rich in tannins and flavonoids.
      • Benefits: Provides organ protection, especially for the digestive system.

    11. Kumari (Aloe barbandensis) Leaf

      • Features: Contains aloin and barbaloin.
      • Benefits: Supports immune function and has antioxidant properties.

    12. Shilajit (Asphaltum) Mineral

      • Features: Packed with fulvic acid and multiple minerals.
      • Benefits: Enhances stamina, cognitive function, and offers organ-protective properties.

    13. Jasad Bhasma (Oxide of zinc) Powder

      • Features: Contains zinc, essential for immune function8.
      • Benefits: Supports immune health and may offer organ protection.

    14. Pippali (Piper longum) Fruit

      • Features: Contains piperine.
      • Benefits: Immune-boosting and supports respiratory health.

    15. Damanaka/Damar (Artemisia nilagirica)

      • Features: Known for its anti-inflammatory and antioxidant properties.
      • Benefits: Supports lung health and boosts immune function.

    References

    1. [Andrographolide and Immune System, Planta Med. 2002] 

    2. [Phytochemical and pharmacological properties of Phyllanthus niruri: a review, Planta Med. 2017] 

    3. [Glycyrrhiza glabra: Medicine over the millennium, Nat Prod Rad. 2005] 

    4. [Efficacy of Ocimum sanctum in respiratory disorders, Ayu. 2015] 

    5. [Immunomodulatory activity of Tinospora cordifolia, Pharmacogn Mag. 2009] 

    6. [Inula racemosa: Chemical composition and medicinal benefits, J Appl Pharm Sci. 2016] 

    7. [The golden spice Curcuma longa: Multitargeting for multiple chronic diseases, Biol Pharm Bull. 2016] 

    8. [The role of zinc in human health, J Altern Complement Med. 2018] 

     

    Research Studies on Ingredients of Reginmune

    Group I. Phytotherapeutic Plant Extracts:

    1. Echinacea extract (Echinacea purpurea, 4.0% total polyphenols) 80mg

      • Features: Contains active substances that enhance the activity of the immune system, relieve pain, reduce inflammation, and have antioxidant effects1.
      • Benefits: Supports the immune response, particularly in fighting colds and respiratory infections1.
    2. Aloe vera 80 mg

      • Features: Contains enzymes, vitamins, amino acids, minerals, and other components that promote wound healing and reduce inflammation2.
      • Benefits: Boosts the immune function, particularly in the gastrointestinal tract2.
    3. Cat's Claw extract (Uncaria tomentosa, bark, more than 3.0% alkaloids) 80 mg

      • Features: Contains oxindole alkaloids that have been reported to stimulate the immune system3.
      • Benefits: Enhances immune response and offers anti-inflammatory properties3.

    Group II. Amino acids:

    1. L-glutamine 140mg

      • Features: An essential amino acid that serves as fuel for immune cells4.
      • Benefits: Supports optimal immune function and intestinal health4.
    2. L-arginine 80mg

      • Features: A semi-essential amino acid that enhances the production of nitric oxide, a molecule that aids immune responses5.
      • Benefits: Supports immune function and wound healing5.
    3. L-lysine HCl 40 mg

      • Features: An essential amino acid known to suppress viral replication6.
      • Benefits: Helps prevent outbreaks of cold sores and other symptoms of herpes virus infections6.
    4. L-Isoleucine 20 mg

      • Features: An essential amino acid that plays a part in the immune function7.
      • Benefits: Supports the production of immune cells and overall immune health7.

    Group III. Vitamins and minerals:

    1. Magnesium gluconate (5.86 %magnesium) 40 mg

      • Features: Essential mineral known to play a role in immune cell activation8.
      • Benefits: Supports optimal immune function and general health8.
    2. Copper gluconate (14.44% copper) 3.5mg

      • Features: An essential trace element involved in various enzyme reactions and immune function9.
      • Benefits: Aids the immune system in defense against bacterial infections9.
    3. Zinc gluconate(14.35% zinc) 25 mg

      • Features: Essential mineral known for its role in cell growth, differentiation, and immune response10.
      • Benefits: Enhances immunity, wound healing, and supports optimal health10.

    Group IV. Biopolymer in the cellular matrix:

    1. Sodium hyaluronate 7.5 mg
      • Features: A salt form of hyaluronic acid that can bind to water and lubricate tissue.
      • Benefits: While its direct impact on immunity isn't widely studied, it's known for joint health and skin hydration, potentially aiding the skin as a barrier against pathogens.

    References

    1. Shah SA, et al. Echinacea in the prevention of induced rhinovirus colds: a meta-analysis. Clin Ther. 2007. 

    2. Langmead L, et al. Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro. Aliment Pharmacol Ther. 2004. 

    3. Piscoya J, et al. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res. 2001. 

    4. Cruzat V, et al. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018. 

    5. Popovic PJ, et al. Arginine and immunity. J Nutr. 2007. 

    6. Griffith RS, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Dermatologica. 1987. 

    7. Li P, et al. Amino acids and immune function. Br J Nutr. 2007. 

    8. Galland L. Magnesium, stress and neuropsychiatric disorders. Magnes Trace Elem. 1991-1992.

    9. Percival SS. Copper and immunity. Am J Clin Nutr. 1998.

    10. Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998.