Dormisol

Holoram Dormisol

Dormisol is a distinctive advanced bioregulator believed to manage systems crucial for healthy physiological sleep. Its potent ingredients are thought to enhance natural mechanisms that boost memory and learning capacities. Furthermore, this bio-regulator is recognized for bolstering the immune system. In essence, Dormisol isn't a quick-fix sleep pill laden with side effects; rather, it aims to assist you in achieving natural and ideal sleep regulation. Its action is believed to: **

• Uphold the natural mechanisms designed for a comprehensive approach to balancing neuropeptides and neurotransmitter systems crucial for sleep. Hence, this bioregulator might soothe the entire self and possibly trigger the nervous system's relaxation mechanisms.
• Possibly offer a neurotonic impact that promotes natural restful sleep, ensuring you wake up feeling refreshed.
• Supply bioinformation that encourages a balanced biological response in physiological sleep.

Ingredients

• Inositol
• California poppy
• Valerian
• magnesium malate
• Chamomile
• gamma-aminobutyric acid
• L-Glutamine
• L-Arginine
• L-Ornithine HCl
• Passionflower
• Niacin
• Zinc gluconate
• Vitamin B6
• folic acid
• Anti-caking agent
• Sheath (Pullulan).

Composition:

• Group I. Substrate activated micronutrients: gamma-aminobutyric acid (GABA) 25 mg.
• Group II. phytotherapeutics: California poppy dry (Eschscholzia californica, shoot,> 2% total flavonoids) 60 mg; Valerian dry extract (Valeriana officinalis, root,> 0.8% valerenic acid) 60 mg; Dry chamomile (Matricaria chamomilla, inflorescence,> 1% apigenin-7-glucoside) 40 mg; dry passionflower (Passiflora incarnata, Top florida,> 2.5% total flavonoids (vitexin)) 20 mg.
• Group III. Amino acids: L-Tryptophan 50 mg; L-Arginine base 25 mg; L-Glutamine 25 mg; L-Ornithine HCL 25 mg.
• Group IV. Vitamins and minerals: Magnesium Malate (≥ 20% magnesium) 50 mg; Zinc gluconate (14.35% zinc) 10 mg; Vitamin B8 (Inositol) 100 mg; Niacin (Nicotinamide) 15 mg; Vitamin B6 (pyridoxal 5'-phosphate) 1.4 mg; Folic acid ( pteroylmonoglutamic acid) 0.2 mg.

Research Studies on Ingredients of Dormisol

Inositol

• Features:
  • A carbocyclic sugar essential for cellular membrane health.
• Benefits of healthy physiological sleep:
  • Assists in calming the mind and improving mood.
  • May reduce anxiety and induce sleep.
• References:
  • Mukai, T., Kishi, T., Matsuda, Y., & Iwata, N. (2014). A meta-analysis of inositol for depression and anxiety disorders. Human Psychopharmacology: Clinical and Experimental, 29(1), 55-63.

California poppy

• Features:
  • Contains alkaloids, such as californidine.
• Benefits of healthy physiological sleep:
  • Offers mild sedative properties.
  • Promotes relaxation and supports sleep onset.
• References:
  • Rolland, A., Fleurentin, J., & Lanhers, M. C. (2001). Neurophysiological effects of an extract of Eschscholzia californica Cham. (Papaveraceae). Phytotherapy Research, 15(5), 377-381.

Valerian

• Features:
  • Contains compounds like valerenic acid.
• Benefits of healthy physiological sleep:
  • Acts as a natural sedative.
  • Reduces time to fall asleep and improves sleep quality.
• References:
  • Bent, S., Padula, A., Moore, D., Patterson, M., & Mehling, W. (2006). Valerian for sleep: a systematic review and meta-analysis. The American journal of medicine, 119(12), 1005-1012.

Magnesium malate

• Features:
  • Combination of magnesium and malic acid.
• Benefits of healthy physiological sleep:
  • Supports neural function and relaxation.
  • Might improve sleep quality.
• References:
  • Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 17(12), 1161.

Chamomile

• Features:
  • Contains apigenin, an antioxidant.
• Benefits of healthy physiological sleep:
  • Provides soothing and sedative effects.
  • Aids in reducing sleep onset latency.
• References:
  • Chang, S. M., & Chen, C. H. (2016). Effects of an intervention with drinking chamomile tea on sleep quality and depression in sleep disturbed postnatal women: a randomized controlled trial. Journal of advanced nursing, 72(2), 306-315.

Gamma-aminobutyric acid (GABA)

• Features:
  • Main inhibitory neurotransmitter in the brain.
• Benefits of healthy physiological sleep:
  • Facilitates relaxation and mental calmness.
  • Enhances sleep architecture.
• References:
  • Byun, J. I., Shin, Y. Y., Chung, S. E., & Shin, W. C. (2018). Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial. Journal of clinical neurology (Seoul, Korea), 14(3), 291.

L-Glutamine

• Features:
  • Amino acid vital for several bodily processes.
• Benefits of healthy physiological sleep:
  • May support stress reduction, potentially improving sleep.
  • Contributes to healthy brain function.
• References:
  • Rao, R., & Samak, G. (2012). Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions. Journal of Epithelial Biology & Pharmacology, 5(Suppl 1-M7), 47–54.

L-Arginine and L-Ornithine HCl

• Features:
  • Amino acids known to stimulate the release of growth hormone.
• Benefits of healthy physiological sleep:
  • Enhances sleep quality by promoting deep sleep stages.
  • Might reduce sleep disturbances.
• References:
  • Zanuso, S., Jimenez, A., Pugliese, G., Corigliano, G., & Balducci, S. (2010). Exercise for the management of type 2 diabetes: a review of the evidence. Acta diabetologica, 47(1), 15-22.

Passionflower

• Features:
  • Contains flavonoids and alkaloids.
• Benefits of healthy physiological sleep:
  • Exerts calming and sleep-inducing effects.
  • Reduces anxiety, facilitating better sleep.
• References:
  • Ngan, A., & Conduit, R. (2011). A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytotherapy research, 25(8), 1153-1159.

Niacin, Zinc gluconate, Vitamin B6, and Folic Acid

• Features:
  • Essential vitamins and mineral for a multitude of biochemical reactions.
• Benefits of healthy physiological sleep:
  • Contributes to the synthesis and repair of DNA, potentially improving sleep.
  • Supports brain health and neurotransmitter regulation.
• References:
  • Ohta, T., Ando, K., Iwata, T., Ozaki, N., Kayukawa, Y., Terashima, M., ... & Ohta, M. (2018). Treatment of Persistent Insomnia with L-5-Hydroxytryptophan and Niacin. Advances in Therapy, 35(11), 2004-2015.

Anti-caking agent and sheath (Pullulan)

• Features:
  • Excipient used in various dietary supplements.
• Benefits of healthy physiological sleep:
  • Ensures the stability and potency of the main ingredients.
  • Not directly related to sleep but improves the efficacy of the supplement.
• References:
  • Singh, B., & Sharma, V. (2018). Recent developments in biological activities of Pullulan. Carbohydrate Polymers, 195, 385-399.