Reginmune – Evidenco

Reginmune

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Reginmune is a bioregulator that enriches the body with essential vitamins, minerals, and nutrition derived from phytotherapeutic plant extracts and other potent ingredients. Utilizing the most pristine and comprehensive natural extracts, it enhances the body's nutritional and energy balance. The formula is designed to potentially bolster the immune system. Its believed mechanisms of action include:

- Fortifying and regulating the body's innate immune defenses.
- Invigorating the natural processes that maintain bodily equilibrium or homeostasis.
- Harmonizing both humoral and cellular immunity to establish a balanced response.
- Orchestrating the immune system's regulation through a specific set of crucial amino acids.

Furthermore, this product is entirely devoid of chemicals and preservatives.

Ingredients

  • Group I. Phytotheraputic Plant Extracts: Echinacea extract (Echinacea purpurea, 4.0% total polyphenols)80mg, Aloe vera80 mg, Cat's Claw extract (Uncariatomentosa, bark, more than 3.0% alkaloids) 80 mg.
  • Group II. Amino acids: L- glutamine 140mg, L-arginine 80mg, L-lysine HCl 40 mg, L- Isoleucine 20 mg.
  • Group III. Vitamins and minerals: Magnesium gluconate (5.86 %magnesium) 40 mg, Copper gluconate (14.44% copper) 3.5mg, Zinc gluconate(14.35% zinc) 25 mg
  • Group IV. Biopolymer in the cellular matrix: Sodium hyaluronate 7.5 mg.
Contents: 60 capsules (720 mg).
Instructions: Once or twice a day, at noon or before lunch, or, as advised by your Doctor.

Research Studies on Ingredients of Reginmune

 

Group I. Phytotherapeutic Plant Extracts:

  1. Echinacea extract (Echinacea purpurea, 4.0% total polyphenols) 80mg

    • Features: Contains active substances that enhance the activity of the immune system, relieve pain, reduce inflammation, and have antioxidant effects1.
    • Benefits: Supports the immune response, particularly in fighting colds and respiratory infections1.
  2. Aloe vera 80 mg

    • Features: Contains enzymes, vitamins, amino acids, minerals, and other components that promote wound healing and reduce inflammation2.
    • Benefits: Boosts the immune function, particularly in the gastrointestinal tract2.
  3. Cat's Claw extract (Uncaria tomentosa, bark, more than 3.0% alkaloids) 80 mg

    • Features: Contains oxindole alkaloids that have been reported to stimulate the immune system3.
    • Benefits: Enhances immune response and offers anti-inflammatory properties3.

Group II. Amino acids:

  1. L-glutamine 140mg

    • Features: An essential amino acid that serves as fuel for immune cells4.
    • Benefits: Supports optimal immune function and intestinal health4.
  2. L-arginine 80mg

    • Features: A semi-essential amino acid that enhances the production of nitric oxide, a molecule that aids immune responses5.
    • Benefits: Supports immune function and wound healing5.
  3. L-lysine HCl 40 mg

    • Features: An essential amino acid known to suppress viral replication6.
    • Benefits: Helps prevent outbreaks of cold sores and other symptoms of herpes virus infections6.
  4. L-Isoleucine 20 mg

    • Features: An essential amino acid that plays a part in the immune function7.
    • Benefits: Supports the production of immune cells and overall immune health7.

Group III. Vitamins and minerals:

  1. Magnesium gluconate (5.86 %magnesium) 40 mg

    • Features: Essential mineral known to play a role in immune cell activation8.
    • Benefits: Supports optimal immune function and general health8.
  2. Copper gluconate (14.44% copper) 3.5mg

    • Features: An essential trace element involved in various enzyme reactions and immune function9.
    • Benefits: Aids the immune system in defense against bacterial infections9.
  3. Zinc gluconate(14.35% zinc) 25 mg

    • Features: Essential mineral known for its role in cell growth, differentiation, and immune response10.
    • Benefits: Enhances immunity, wound healing, and supports optimal health10.

Group IV. Biopolymer in the cellular matrix:

  1. Sodium hyaluronate 7.5 mg
    • Features: A salt form of hyaluronic acid that can bind to water and lubricate tissue.
    • Benefits: While its direct impact on immunity isn't widely studied, it's known for joint health and skin hydration, potentially aiding the skin as a barrier against pathogens.

References

  1. Shah SA, et al. Echinacea in the prevention of induced rhinovirus colds: a meta-analysis. Clin Ther. 2007. 

  2. Langmead L, et al. Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro. Aliment Pharmacol Ther. 2004. 

  3. Piscoya J, et al. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res. 2001. 

  4. Cruzat V, et al. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018. 

  5. Popovic PJ, et al. Arginine and immunity. J Nutr. 2007. 

  6. Griffith RS, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Dermatologica. 1987. 

  7. Li P, et al. Amino acids and immune function. Br J Nutr. 2007. 

  8. Galland L. Magnesium, stress and neuropsychiatric disorders. Magnes Trace Elem. 1991-1992.

  9. Percival SS. Copper and immunity. Am J Clin Nutr. 1998.

  10. Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998.